Last month, the biopharmaceutical company Gilead shared groundbreaking results from a recent clinical trial (PURPOSE1) for long-acting injectable HIV prevention. The twice-yearly injectable drug, lenacapavir, provided total protection from HIV for a test group of 2,134 women in Uganda and South Africa. While lenacapavir has been used to treat multi-drug resistant HIV since 2022, this trial marks the first usage as pre-exposure prophylaxis (PrEP). PrEP is one tool to prevent the virus, and refers to anti-retroviral medication taken by people who do not have HIV to reduce the risk of contracting it through sexual transmission or injection drug use. These new findings offer immense promise for the future of PrEP as a global tactic to protect young women from contracting HIV. 

Mildred is a fish trader in Kenya. I met her a few years ago, when I was conducting research. (“Mildred” is not her real name; I promised all my participants anonymity as I worked.) She mentors, trains, and educates young women on how to dry, gut, fry fish, and run successful fish businesses.  

LGBTIQ+ organizations and activists increasingly speak of “queering” systems such as global climate action, global refugee systems, or humanitarian response. Sometimes, this is a rhetorical reboot of existing strategies for increasing inclusion, with ‘queer’ used as a reclaimed shorthand for LGBTIQ+ people. The process of tweaking existing social and economic systems to address climate change and security threats should also certainly ensure the inclusion of LGBTQI+ people.

A window into what we are reading at the Wilson Center’s Environmental Change and Security Program

Renewable Energy Needs a Social Vision (Mongabay)

The Zapotec of the Isthmus of Tehuantepec have accused energy giant EDF (Électricité de France) of causing human rights abuses while building wind farms in Oaxaca state. They also claim the company intimidated and harassed social movements who opposed this construction on their ancestral lands. The Zapotec are indigenous peoples of Mexico who call themselves Bën Za or “The People”—and after three years of struggle and stalling tactics by EDF’s legal representatives, French courts have authorized their civil case filing at last. 

“There is a really important need in talking about knowledge equity around what is actually happening with the climate crisis, and what happens to maternal [and] neo-natal health as a result of it,” said Neha Mankani, Midwifery Association Capacity Assessment Strengthening Lead at the International Confederation of Midwives, at a recent Wilson Center event titled “Midwives Are Key to Climate Resilience.”

Environmental shocks have been linked to significant changes in human migration around the world. Yet the large literature on environmental change and migration to date has primarily focused on working-age adults, working largely on the assumption that climatic impacts are most likely to influence labor migration.

In an era where water scarcity and disputes over water rights increasingly shape global politics, understanding the nexus between water and peace is more critical than ever. Recent events such as the border clashes between Kyrgyzstan and Tajikistan, or continued tensions between Egypt, Ethiopia, and Sudan over the Nile River’s usage, underscore the urgent need for comprehensive strategies to address both the hydrological and social dimensions of water management.