Over the last four decades, contracting HIV has been transformed from a fatal diagnosis to a manageable chronic illness. Political will and financial commitments have reduced new HIV infections worldwide by 39 percent since 2010. However, much work still is needed to meet global targets of preventing new cases of HIV and reducing AIDS-related deaths. Marginalized communities, including women and girls, face countless barriers which hinder progress towards comprehensive HIV prevention across the planet.

Maternal health among adolescents in low- and middle-income countries (LMICs) remains a largely unexplored and frequently neglected area within the public health field. Adolescent birth rates remain disproportionately high in LMICs, accounting for approximately 97% of all adolescent births globally. The prevalence of child marriage, poverty, gender-based violence, and limited access to and utilization of contraceptive methods all contribute to this startling statistic.

Each day, almost 800 women die from preventable causes related to pregnancy and childbirth. A maternal death occurs every two minutes. Maternal mortality is defined as the death of a woman from complications of pregnancy or childbirth that occur during the pregnancy or within 6 weeks after the pregnancy ends.*

A window into what we are reading at the Wilson Center’s Environmental Change and Security Program

Mpox Outbreak a Global Health Emergency, Again (The Washington Post) 

Various rapidly spreading mpox strains in Central and East African countries have led the World Health Organization (WHO) to declare the viral infection as a global health emergency. More than 15,000 people have been infected this year alone, with over 500 deaths reported. Mpox is transmitted largely through exposure to infected animals, as well as via skin-to-skin or sexual contact, and it disproportionately affects heterosexuals and sex workers.

A window into what we are reading at the Wilson Center’s Environmental Change and Security Program

Worsening Health Conditions in War-Torn Gaza (BBC) 

Water infrastructure in Gaza was already weak before the beginning of the war in 2023, but intensified conflict and siege of critical infrastructure the damage wreaked by Israel’s military forces on critical infrastructure (including water, energy, and food), has left 70% of the people in Gaza exposed to salinated and contaminated water. Traces of polio have been found in wastewater flowing both between displacement camp tents and in inhabited areas, and experts suggest that this water might be circulating. 

Last month, the biopharmaceutical company Gilead shared groundbreaking results from a recent clinical trial (PURPOSE1) for long-acting injectable HIV prevention. The twice-yearly injectable drug, lenacapavir, provided total protection from HIV for a test group of 2,134 women in Uganda and South Africa. While lenacapavir has been used to treat multi-drug resistant HIV since 2022, this trial marks the first usage as pre-exposure prophylaxis (PrEP). PrEP is one tool to prevent the virus, and refers to anti-retroviral medication taken by people who do not have HIV to reduce the risk of contracting it through sexual transmission or injection drug use. These new findings offer immense promise for the future of PrEP as a global tactic to protect young women from contracting HIV. 

Young people should be able to hold public officials and service providers accountable for meeting their needs and rights. And this principle—known as youth social accountability—can also have a ripple effect on the health and wellbeing of young people themselves by enhancing the quality of health services and fostering more positive interactions with adolescents within health systems.