“Never let a good crisis go to waste,” said Winston Churchill. Like other acute stressors, the COVID-19 pandemic acts as a multiplier of chronic or pre-existing vulnerabilities, such as the challenges of servicing rapidly growing informal populations, particularly in urban settings. This multiplier effect may accelerate water insecurity at unprecedented levels. However, together with UNESCO Intergovernmental Hydrological Program (IHP), we’re reflecting on the possibility that COVID-19 can act as an accelerator of positive action toward achieving Sustainable Development Goal 6 on water. The nexus between issues and urban water security is particularly important.